A practical protocol for synthesising aggregation-prone peptides, drawn from 1,400+ published sources
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Investigation of commercially available resins for the automated flow synthesis of difficult or long peptide sequences
A versatile “Synthesis Tag” (SynTag) for the chemical synthesis of aggregating peptides and proteins
A Versatile “Synthesis Tag” (SynTag) for the Chemical Synthesis of Aggregating Peptides and Proteins
Development of ArgTag for Scalable Solid-Phase Synthesis of Aggregating Peptides
Development of ArgTag for scalable solid-phase synthesis of aggregating peptides
Development ofArgTag for Scalable Solid-Phase Synthesisof Aggregating Peptides
A versatile “Synthesis Tag” (SynTag) for the chemical synthesis of aggregating peptides and proteins
Robert C. Sheppard (1932‐2019)
An Original PEG‐Functionalized PS Resin Enables Synthesis of Difficult Peptides: Application to Tirzepatide
Development of ArgTag for scalable solid-phase synthesis of aggregating peptides
Synthesis of Antioxidant Peptide SCAP1 (Leu-Ala-Asn-Ala-Lys)
Evaluation of 4-<i>tert</i>-Butyl-Benzhydrylamine Resin (BUBHAR) as an Alternative Solid Support for Peptide Synthesis
Solid-State Nuclear Magnetic Resonance of Protein Characterization at Fast Magic Angle Spinning
Thirteen decades of peptide synthesis: key developments in solid phase peptide synthesis and amide bond formation utiliz
Recombinant and Synthetic Affibodies Function Comparably for Modulating Protein Release.
Solid-Phase Synthesis of Difficult Purine-Rich PNAs through Selective Hmb Incorporation: Application to the Total Synthe
Bypassing Osmotic Shock Dilemma in a Polystyrene Resin Using the Green Solvent Cyclopentyl methyl Ether (CPME): A Morpho
Solid phase peptide synthesis: new resin and new protecting group.
Optimization of peptide synthesis time and sustainability using novel eco-friendly binary solvent systems with induction
<i>N</i>‐Butylpyrrolidinone for Solid‐Phase Peptide Synthesis is Environmentally Friendlier and Synthetically Better tha
Greener solvents for solid-phase synthesis
Circular Aqueous Fmoc/t-Bu Solid-Phase Peptide Synthesis.
Simple method to assess stability of immobilized peptide ligands against proteases
Solid-Phase Synthesis of Well-Defined Multiblock Copolymers by Atom Transfer Radical Polymerization.
Factors influencing on-resin depsipeptide bond formation: case studies on daptomycin- and brevicidine-derived sequences.
Solid Phase Synthesis of Casimersen and Its 3ʹ-end Modification for Therapeutic Benefits
Solid phase peptide synthesis: new resin and new protecting group.
Silica-Assisted Solid-Phase Peptide Synthesis (SiPPS).
Optimized Stepwise Synthesis of the API Liraglutide Using BAL Resin and Pseudoprolines.
OctaGel Resin - A New PEG-PS-based Solid Support for Solid-Phase Peptide Synthesis
Mechanistic Study of Diketopiperazine Formation during Solid-Phase Peptide Synthesis of Tirzepatide.
Preparation of tri(ethylene glycol) grafted core-shell type polymer support for solid-phase peptide synthesis.
N-Butylpyrrolidinone is an equally good solvent as N,N-dimethylformamide for microwave assisted solid phase peptide synt
Toward a Green SPPS: The Use of an Innovative Mesoporous pDVB Support for Environmentally Friendly Solvents.
Synthese von Glycoformen des humanen Erythropoietins
A backbone amide protecting group for overcoming difficult sequences and suppressing aspartimide formation.
Rhodiasolv PolarClean – a greener alternative in solid-phase peptide synthesis
Synthesis, 18F-labelling and radiopharmacological characterisation of the C-terminal 30mer of Clostridium perfringens en
Improving 2-Chlorotrityl Chloride (2-CTC) Resin Activation.
Ultrasonic-Assisted Solid-Phase Peptide Synthesis of DOTA-TATE and DOTA-linker-TATE Derivatives as a Simple and Low-Cost
Computer vision as a new paradigm for monitoring of solution and solid phase peptide synthesis.
A Rapid Manual Solid Phase Peptide Synthesis Method for High-Throughput Peptide Production.
The aspartimide problem persists: Fluorenylmethyloxycarbonyl‐solid‐phase peptide synthesis (Fmoc‐SPPS) chain termination
Evaluation of unexpected protecting group removal in solid-phase peptide synthesis: Quantified using continuous flow met
An Isodipeptide Building Block for Microwave-Assisted Solid-Phase Synthesis of Difficult Sequence-Containing Peptides.
Microwave-Assisted Green Solid-Phase Peptide Synthesis Using γ-Valerolactone (GVL) as Solvent
Greening the Solid-Phase Peptide Synthesis Process. 2-MeTHF for the Incorporation of the First Amino Acid and Precipitat
Green Solvent Mixtures for Solid-Phase Peptide Synthesis: A Dimethylformamide-Free Highly Efficient Synthesis of Pharmac
Peptides, solid-phase synthesis and characterization: Tailor-made methodologies
Efficient synthesis of CN2097 using in situ activation of sulfhydryl group.
Sustainable Ultrasound-Assisted Solid-Phase peptide synthesis (SUS-SPPS): Less Waste, more efficiency.
Automated solid-phase synthesis of metabolically stabilized triazolo-peptidomimetics.
Triethyl phosphate (TEP) – dimethylsulfoxide (DMSO), as a green solvent mixture for solid-phase peptide synthesis (SPPS)
An entirely fmoc solid phase approach to the synthesis of daptomycin analogs.
Bacterial expression and/or solid phase peptide synthesis of 20-40 amino acid long polypeptides and miniproteins, the ca
AN IMPROVED SYNTHESIS OF PENTAPEPTIDE (SCAP1e) USING SOLID-PHASE METHOD WITH REDUCED RESIN LOADING TIME
Solid-State Nuclear Magnetic Resonance of Protein Characterization at Fast Magic Angle Spinning
Solid phase peptide synthesis: new resin and new protecting group.
Solid phase peptide synthesis: new resin and new protecting group.
Pitfalls in the synthesis of fluorescent methotrexate oligopeptide conjugates.
Tetrahydropyranyl Backbone Protection for Enhanced Fmoc Solid-Phase Peptide Synthesis.
Synthesis of O-Acyl Isopeptides: Stepwise and Convergent Solid-Phase Synthesis.
Troubleshooting When Using γ-Valerolactone (GVL) in Green Solid-Phase Peptide Synthesis
Automatic procedures for the synthesis of difficult peptides using oxyma as activating reagent: A comparative study on t
Investigation of antigen loading in synthetic peptide vaccines for cancer immunotherapy
Improving Fmoc Solid Phase Synthesis of Human Beta Defensin 3.
Solid phase peptide synthesis: new resin and new protecting group.
Solid-Phase Synthesis of a Seventh-Generation Inverse Poly(amidoamine) Dendrimer: Importance of the Loading Ratio on the
Protocol for efficient solid-phase synthesis of peptides containing 1-hydroxypyridine-2-one (1,2-HOPO).
Epimerization-Free Preparation of C-Terminal Cys Peptide Acid by Fmoc SPPS Using Pseudoproline-Type Protecting Group.
Expanding the scope of sustainable peptide synthesis through post-linear synthesis reactions.
Successful synthesis of a glial-specific blood-brain barrier shuttle peptide following a fragment condensation approach
Perfluoro-tert-butanol for selective on-resin detritylation: a mild alternative to traditionally used methods.
Development of a Single-Chain Peptide Agonist of the Relaxin-3 Receptor Using Hydrocarbon Stapling.
Solution Phase Peptide Synthesis: The Case of Biphalin.
Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay.
Solution Phase Peptide Synthesis: The Case of Biphalin.
Water-Based Solid-Phase Peptide Synthesis without Hydroxy Side Chain Protection.
Stain Protocol for the Detection of N-Terminal Amino Groups during Solid-Phase Peptide Synthesis.
Toward sustainable solid-phase peptide synthesis strategy – in situ Fmoc removal
Solid phase peptide synthesis: new resin and new protecting group.
Solid-Phase Synthesis of Oligopeptides Containing Sterically Hindered Amino Acids on Nonswellable Resin Using 3-Nitro-1,
Immobilized acyl-transfer molecular reactors enable the solid-phase synthesis of sterically hindered peptides.
2-Methyltetrahydrofuran and cyclopentyl methyl ether for green solid-phase peptide synthesis.
Photo-Accelerated Synthesis of Oligo(triazole amide)s.
A general method for preparation of <i>N</i>‐Boc‐protected or <i>N</i>‐Fmoc‐protected α,β‐didehydropeptide building bloc
Evaluation of 1H-Triazole-1-[N,N'-Bis(tert-butoxycarbonyl)]carboxamidine in Solution-Phase and On-Resin Guanidinyla
Performance Comparison of Three Chemical Vapor Deposited Aminosilanes in Peptide Synthesis: Effects of Silane on Peptide
<i>tert</i>-Butylethylcarbodiimide as an Efficient Substitute for Diisopropylcarbodiimide in Solid-Phase Peptide Synthes
Triethyl phosphate (TEP) as a green solvent for solid-phase peptide synthesis (SPPS)
Green Solid-Phase Peptide Synthesis (GSPPS) 3. Green Solvents for Fmoc Removal in Peptide Chemistry
Solid phase peptide synthesis: new resin and new protecting group.
Resin Swelling in Mixed Solvents Analysed using Hansen Solubility Parameter Space.
Synthesis of [1-8-NαC]-zanriorb A1, alanine-containing analogues, and their cytotoxic and anti-inflammatory activity.
Regeneration of aged DMF for use in solid-phase peptide synthesis.
Green Solid-Phase Peptide Synthesis 2. 2-Methyltetrahydrofuran and Ethyl Acetate for Solid-Phase Peptide Synthesis under
N -Butylpyrrolidinone as Alternative Solvent for Solid-Phase Peptide Synthesis
Application of a new green protocol in solid-phase peptide synthesis: identification of a new green solvent mixture comp
Solid phase peptide synthesis: new resin and new protecting group.
Synthesis of Tetra-ortho-Methoxylated Azobenzene Photoswitches via Sequential Catalytic C−H Activation and Methoxylation
Morpholine, a strong contender for Fmoc removal in solid-phase peptide synthesis.
Dipropylamine for 9-Fluorenylmethyloxycarbonyl (Fmoc) Deprotection with Reduced Aspartimide Formation in Solid-Phase Pep
Optimized Fmoc-Removal Strategy to Suppress the Traceless and Conventional Diketopiperazine Formation in Solid-Phase Pep
Fmoc-Removal with Pyrrolidine Expands the Available Solvent Space in Green Solid-Phase Peptide Synthesis
Solid phase peptide synthesis: new resin and new protecting group.
A Novel Method for Liraglutide Synthesis and Purification
Brønsted Acid-Lewis Acid (BA-LA) Induced Final Deprotection/Peptide Resin Cleavage in Fmoc/t-Bu Solid-Phase Peptide Synt
A new procedure for thioester deprotection using thioglycolic acid in both homogeneous and heterogeneous phase.
Photocatalytic C-X Bond Cleavage Facilitates Peptide Synthesis.
Removable dialkoxybenzyl linker for enhanced HPLC purification of peptide hydrazides
The development of a dedicated polymer support for the solid-phase oligosaccharide synthesis.
Solid-State Nuclear Magnetic Resonance of Protein Characterization at Fast Magic Angle Spinning
Immobilization of Trifluoromethyl-Substituted Pyridine-Oxazoline Ligand and Its Application in Asymmetric Continuous Flo
Development of a novel, automated, robotic system for rapid, high-throughput, parallel, solid-phase peptide synthesis
Aqueous solid-phase peptide synthesis (ASPPS): A novel concept of peptide synthesis
Automated flow peptide synthesis
Modelling Resin Swelling in Mixed Solvents and Its Applications
A Study of Zwitterionic Polypeptide-Protein Conjugates
Reflections on a Copenhagen–Minneapolis Axis in Bioorganic Chemistry
Synthetic Evaluation of Standard and Microwave-Assisted Solid Phase Peptide Synthesis of a Long Chimeric Peptide Derived
Solid phase peptide synthesis: new resin and new protecting group.
Caps - Turns - Loops: Designing Better β-Hairpins
Dynamic covalent chemistry at the solution: Surface interface
Modelling Resin Swelling in Mixed Solvents and Its Applications
Solid phase peptide synthesis: new resin and new protecting group.
Synthetic Study on ADP-ribosylation
Efficient Synthesis of Peptides with 4-Methylpiperidine as Fmoc Removal Reagent by Solid Phase Synthesis
Cyclizing Painkillers: Development of Backbone-Cyclic TAPS Analogs.
Peptide synthesis: ball-milling, in solution, or on solid support, what is the best strategy?
A solid-phase approach for the synthesis of α-aminoboronic acid peptides.
Real-time monitoring of solid-phase peptide synthesis using a variable bed flow reactor.
Efficient automated solid-phase synthesis of recognition-encoded melamine oligomers.
Automated flow peptide synthesis
Modelling Resin Swelling in Mixed Solvents and Its Applications
A Study of Zwitterionic Polypeptide-Protein Conjugates
Solid phase peptide synthesis: new resin and new protecting group.
Caps - Turns - Loops: Designing Better β-Hairpins
Radiometallation and photo-triggered release of ready-to-inject radiopharmaceuticals from the solid phase.
Automated flow peptide synthesis
Modelling Resin Swelling in Mixed Solvents and Its Applications
A Study of Zwitterionic Polypeptide-Protein Conjugates
Chemical synthesis of switchable peptide-based nanopores: from ion channels to bio-inspired materials
Automated flow peptide synthesis
Modelling Resin Swelling in Mixed Solvents and Its Applications
A Study of Zwitterionic Polypeptide-Protein Conjugates
Protocol for Facile Synthesis of Fmoc-N-Me-AA-OH Using 2-CTC Resin as Temporary and Reusable Protecting Group.
Harnessing polarity and viscosity to identify green binary solvent mixtures as viable alternatives to DMF in solid-phase
Replacing DMF in solid-phase peptide synthesis: varying the composition of green binary solvent mixtures as a tool to mi
Synthesis of Peptoids Containing Multiple Nhtrp and Ntrp Residues: A Comparative Study of Resin, Cleavage Conditions and
Automated flow peptide synthesis
Modelling Resin Swelling in Mixed Solvents and Its Applications
A Study of Zwitterionic Polypeptide-Protein Conjugates
Solid phase peptide synthesis: new resin and new protecting group.
Caps - Turns - Loops: Designing Better β-Hairpins
Modelling Resin Swelling in Mixed Solvents and Its Applications
Synthesis of disulfide-rich heterodimeric peptides through an auxiliary N, N-crosslink
Heterogenous catalysis for oxygen tolerant photoredox atom transfer radical polymerization and small-molecule dehalogena
Isoacylpeptide Method for Long-Chain and Difficult Sequence-Containing Peptide Preparation
Solid phase peptide synthesis: new resin and new protecting group.
Synthetic Study on ADP-ribosylation
5-Amino-3-methyl-Isoxazole-4-carboxylic Acid as a Novel Unnatural Amino Acid in the Solid Phase Synthesis of α/β-Mixed P
Establishment of One-Pot Disulfide-Driven Cyclic Peptide Synthesis with a 3-Nitro-2-pyridinesulfenate.
A biocompatible stapling reaction for in situ generation of constrained peptides.
Greening the synthesis of peptide therapeutics: an industrial perspective.
Musaimi, Othman Al; Tomkins
othman.almusaimi@newcastle.ac.uk
Draft exists in humblebee/green solvents for solid phase peptide synthesis
"Evidentia Labs - DEG-PS resin backbone and loading"
Torre, Beatriz G. de la
garciadelatorreb@ukzn.ac.za
Amino-Li-Resin—A Fiber Polyacrylamide Resin for Solid-Phase Peptide Synthesis
ViewChristian P R; Seitz, Oliver
oliver.seitz@chemie.hu-berlin.de
Draft exists in humblebee/green solvents for solid phase peptide synthesis
"Evidentia Labs — MUC5AC synthesis on TentaGel"
paul.harris@auckland.ac.nz
Efficient synthesis and characterisation of the amyloid beta peptide, Aβ<sub>1–42</sub>, using a double linker system
jayavarkey@yahoo.com
Introductory Chapter: Peptide Synthesis
perczel.andras@ttk.elte.hu
Acetyl group for proper protection of β-sugar-amino acids used in SPPS.
k.djanashvili@tudelft.nl
Solid-phase synthesis and evaluation of tumour-targeting phenylboronate-based MRI contrast agents.
dasan.jaradat@bau.edu.jo
Advances in solid-phase peptide synthesis in aqueous media (ASPPS)
john.lopez@novartis.com
Revisiting NO2 as Protecting Group of Arginine in Solid-Phase Peptide Synthesis.
garciadelatorreb@ukzn.ac.za
Scope and Limitations of γ-Valerolactone (GVL) as a Green Solvent to be Used with Base for Fmoc Removal in Solid Phase P
Michael.north@york.ac.uk
The greening of peptide synthesis
timaoka@res.titech.ac.jp
Synthesis of atom-precise supported metal clusters via solid-phase peptide synthesis.
y.kim@yonsei.ac.kr
Solid-phase synthesis and pathological evaluation of pyroglutamate amyloid-β3-42 peptide
walter.cabri@unibo.it
Solid phase peptide synthesis using side-chain unprotected arginine and histidine with Oxyma Pure/TBEC in green solvents
sylwia.freza@ug.edu.pl
Synthesis of Novel Arginine Building Blocks with Increased Lipophilicity Compatible with Solid-Phase Peptide Synthesis.
chuanzheng.zhou@nankai.edu.cn
Suppression of alpha-carbon racemization in peptide synthesis based on a thiol-labile amino protecting group.
a.tornesello@istitutotumori.na.it
Solid Phase Formylation of N-Terminus Peptides.
suniljacob07@gmail.com
Synthesis of Biologically Active Peptides using Newly Designed N-Vinyl Pyrrolidone Incorporated Flexible Cross linked Po
eric.biron@pha.ulaval.ca
Synthesis, antimicrobial activity and conformational analysis of the class IIa bacteriocin pediocin PA-1 and analogs the
yuenty@ices.a-star.edu.sg
Stereoisomerism of stapled peptide inhibitors of the p53-Mdm2 interaction: an assessment of synthetic strategies and act
albericio@ukzn.ac.za
Solid-Phase Synthesis of Head to Side-Chain Tyr-Cyclodepsipeptides Through a Cyclative Cleavage From Fmoc-MeDbz/MeNbz-re
hilda.garay@cigb.edu.cu
Structural Characterization of the Dimers and Selective Synthesis of the Cyclic Analogues of the Antimicrobial Peptide C
wanglin@bmi.ac.cn
Synthesis of Cyclic Peptides in SPPS with Npb-OH Photolabile Protecting Group.
ataguchi@toyaku.ac.jp
[Development of Synthetic Methodology for Mid-size Peptide Based on Disulfide Bond Formation].
abeck-sickinger@uni-leipzig.de
On-resin Diels-Alder reaction with inverse electron demand: an efficient ligation method for complex
jan.pawlas@polypeptide.com
1,4-Benzenedimethanethiol (1,4-BDMT) as a scavenger for greener peptide resin cleavages.
j.r.baker@ucl.ac.uk
A novel thiol-labile cysteine protecting group for peptide synthesis based on a pyridazinedione (PD)
magnus.rueping@kaust.edu.sa
Resonant acoustic mixing enables solvent-less amide coupling in solid-phase peptide synthesis
piotr.mucha@ug.edu.pl
Solid-Phase Synthesis Approaches and U-Rich RNA-Binding Activity of Homotrimer Nucleopeptide Contain
marie.prochiner@stud.uni-heidelberg.de
Ultrasound-Assisted Solid-Phase Affibody Synthesis Using ZEGFR:1907 as an Example-Superior to the Co
guoqp@lzu.edu.cn
Efficient solid-phase synthesis and structural characterization of segetalins A-H, J and K.
oliver.seitz@chemie.hu-berlin.de
Impact of Glycoclustering on Stiffening of MUC5AC Peptides Revealed by High‐Efficiency Synthesis
jon.collins@cem.com
Total wash elimination for solid phase peptide synthesis
othman.almusaimi@newcastle.ac.uk
Towards green, scalable peptide synthesis: leveraging DEG-crosslinked polystyrene resins to overcome
chris.serpell@ucl.ac.uk
Selection of optimised ligands by fluorescence-activated bead sorting
gserra@fq.edu.uy
First total synthesis of versicotide A, B and C
nina.hartrampf@chem.uzh.ch
A robust data analytical method to investigate sequence dependence in flow-based peptide synthesis
pasquale.marino@unibas.it
Dipropyleneglycol Dimethylether, New Green Solvent for Solid-Phase Peptide Synthesis: Further Challe
kusui@konan-u.ac.jp
Novel Purification Process for Amyloid Beta Peptide(1-40)
oliver.seitz@chemie.hu-berlin.de
Impact of Glycoclustering on Stiffening of MUC5AC Peptides Revealed by High‐Efficiency Synthesis
oliver.seitz@chemie.hu-berlin.de
Impact of Glycoclustering on Stiffening of MUC5AC Peptides Revealed by High‐Efficiency Synthesis
oliver.seitz@chemie.hu-berlin.de
Impact of Glycoclustering on Stiffening of MUC5AC Peptides Revealed by High‐Efficiency Synthesis
oliver.seitz@chemie.hu-berlin.de
Impact of Glycoclustering on Stiffening of MUC5AC Peptides Revealed by High‐Efficiency Synthesis
oliver.seitz@chemie.hu-berlin.de
Impact of Glycoclustering on Stiffening of MUC5AC Peptides Revealed by High‐Efficiency Synthesis
oliver.seitz@chemie.hu-berlin.de
Impact of Glycoclustering on Stiffening of MUC5AC Peptides Revealed by High‐Efficiency Synthesis
oliver.seitz@chemie.hu-berlin.de
Impact of Glycoclustering on Stiffening of MUC5AC Peptides Revealed by High‐Efficiency Synthesis
oliver.seitz@chemie.hu-berlin.de
Impact of Glycoclustering on Stiffening of MUC5AC Peptides Revealed by High‐Efficiency Synthesis